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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2753
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta1
Name: glutathione S-transferase alpha 1
Acc ID: CHEBI:9570
Term: Thiotepa
Definition: An aziridine that has formula C6H12N3PS.
Chemical ID: MESH:D013852
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta1affects exportISOGSTA1 (Homo sapiens)6480464CTDGSTA1 gene SNP affects the export of ThiotepaPMID:19076156
Gsta1affects response to substanceISOGSTA1 (Homo sapiens)6480464CTDGSTA1 protein affects the susceptibility to ThiotepaPMID:19076156
Gsta1multiple interactionsISOGSTA1 (Homo sapiens)6480464CTDGSTA1 protein affects the metabolism of [Thiotepa co-treated with Glutathione]PMID:7712478
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