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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3747
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serpina3n
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3N
Acc ID: CHEBI:9566
Term: thioridazine
Definition: A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.
Chemical ID: MESH:D013881
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpina3nincreases expressionISOSERPINA3 (Homo sapiens)6480464CTDThioridazine results in increased expression of SERPINA3 mRNAPMID:15342952 PMID:17175557
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