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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589491
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sepsecs
Name: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Acc ID: CHEBI:9546
Term: thimerosal
Definition: An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
Chemical ID: MESH:D013849
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sepsecsincreases expressionISOSEPSECS (Homo sapiens)6480464CTDThimerosal results in increased expression of SEPSECS mRNAPMID:27188386
Sepsecsmultiple interactionsISOSEPSECS (Homo sapiens)6480464CTD[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEPSECS mRNAPMID:27188386
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