GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Crbn | affects binding | EXP | | 6480464 | CTD | Thalidomide binds to [CRBN protein binds to DDB1 protein] | PMID:25108355 | Crbn | affects binding | ISO | CRBN (Homo sapiens) | 6480464 | CTD | Thalidomide binds to [SALL4 protein binds to CRBN protein]; Thalidomide binds to CRBN protein | PMID:27751757 PMID:30067223 | Crbn | affects response to substance | ISO | CRBN (Homo sapiens) | 6480464 | CTD | CRBN gene SNP affects the susceptibility to Thalidomide | PMID:27751757 | Crbn | multiple interactions | ISO | CRBN (Homo sapiens) | 6480464 | CTD | Thalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein] | PMID:25043012 | |
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