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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1616839
Species: Mus musculus
RGD Object: Gene
Symbol: Eif2ak2
Name: eukaryotic translation initiation factor 2-alpha kinase 2
Acc ID: CHEBI:94807
Term: acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester
Definition: A carboxylic ester that has formula C12H9N3O5S.
Chemical ID: MESH:C041747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2ak2multiple interactionsISOEIF2AK2 (Homo sapiens)6480464CTDIFNA2 protein promotes the reaction [nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of and results in increased activity of EIF2AK2 protein]]; nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of and results in increased activity of EIF2AK2 protein]; nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of EIF2A protein]PMID:19664635
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