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REFERENCE - CHEMICAL INTERACTIONS REPORT

RGD ID: 5130957
Species: All species
RGD Object: Reference
Acc ID: CHEBI:9467
Term: tetrabenazine
Definition: A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia.
Chemical ID: MESH:D013747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc18a2affects bindingEXP 5130957RGDTetrabenazine binds to Slc8a2 protein 
SLC18A2affects bindingISORGD:36945130957RGDTetrabenazine binds to Slc8a2 protein 
Slc18a2affects bindingISORGD:36945130957RGDTetrabenazine binds to Slc8a2 protein 
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