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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:9464
Term: testosterone enanthate
Definition: An enanthate ester that has formula C26H40O3.
Chemical ID: MESH:C004648
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1decreases expressionEXP 6480464CTDtestosterone enanthate results in decreased expression of ESR1 mRNAPMID:21427060
Esr1increases activityEXP 6480464CTDtestosterone enanthate results in increased activity of ESR1 proteinPMID:12504345
Esr1increases expressionEXP 6480464CTDtestosterone enanthate results in increased expression of ESR1 mRNA; testosterone enanthate results in increased expression of ESR1 proteinPMID:21729141
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