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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10106
Species: Mus musculus
RGD Object: Gene
Symbol: Adrb1
Name: adrenergic receptor, beta 1
Acc ID: CHEBI:9449
Term: terbutaline
Definition: A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
Chemical ID: MESH:D013726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adrb1multiple interactionsISOAdrb1 (Rattus norvegicus)6480464CTDTerbutaline inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]PMID:8096834
Adrb1multiple interactionsISOADRB1 (Homo sapiens)6480464CTDTerbutaline binds to and results in decreased activity of ADRB1 protein; Terbutaline binds to and results in increased activity of ADRB1 protein mutant form; Terbutaline inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Terbutaline inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]PMID:14730417 PMID:16648137 PMID:8096834
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