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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304965
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rhoc
Name: ras homolog family member C
Acc ID: CHEBI:9448
Term: terbinafine
Definition: A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections.
Chemical ID: MESH:C041359
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rhocincreases localizationISORGD:13127116480464CTDterbinafine results in increased localization of RHOC proteinPMID:17172416
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