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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10123
Species: Mus musculus
RGD Object: Gene
Symbol: Agtr1b
Name: angiotensin II receptor, type 1b
Acc ID: CHEBI:9434
Term: telmisartan
Definition: A member of the class of benzimidazoles used widely in the treatment of hypertension.
Chemical ID: MESH:C084178
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1bmultiple interactionsEXP 6480464CTDtelmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]PMID:17620961
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