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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:9400
Term: tangeretin
Definition: A pentamethoxyflavone flavone with methoxy groups at positions 4', 5, 6 , 7 and 8.
Chemical ID: MESH:C059006
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:25036480464CTDtangeretin inhibits the reaction [9, 10-Dimethyl-1, 2-benzanthracene results in decreased expression of NQO1 mRNA], tangeretin inhibits the reaction [9, 10-Dimethyl-1, 2-benzanthracene results in decreased expression of NQO1 protein]

PMID:24995432
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.