GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | decreases activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | tangeretin results in decreased activity of ABCB1 protein | PMID:30790579 | Abcb1a | decreases expression | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | tangeretin results in decreased expression of ABCB1 protein | PMID:34217736 | Abcb1a | increases activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | tangeretin results in increased activity of ABCB1 protein | PMID:34217736 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; tangeretin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; tangeretin inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Verapamil inhibits the reaction [tangeretin results in increased activity of ABCB1 protein] | PMID:30790579 PMID:34217736 | | ||||||||||||||||||||||
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