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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316077
Species: Homo sapiens
RGD Object: Gene
Symbol: TFB2M
Name: transcription factor B2, mitochondrial
Acc ID: CHEBI:9381
Term: T-2 toxin
Definition: A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals.
Chemical ID: MESH:D013605
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TFB2Maffects expressionISOTfb2m (Rattus norvegicus)6480464CTDT-2 Toxin affects the expression of TFB2M mRNAPMID:29870751
TFB2Mincreases expressionISOTfb2m (Rattus norvegicus)6480464CTDT-2 Toxin results in increased expression of TFB2M mRNAPMID:36863559
TFB2Mmultiple interactionsISOTfb2m (Rattus norvegicus)6480464CTDGABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]PMID:36863559
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