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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10505
Species: Mus musculus
RGD Object: Gene
Symbol: Ednrb
Name: endothelin receptor type B
Acc ID: CHEBI:93310
Term: N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide
Definition: A benzamide that has formula C15H8ClF6NO2.
Chemical ID: MESH:C492919
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ednrbmultiple interactionsISOEdnrb (Rattus norvegicus)6480464CTDN-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Smoke results in increased expression of EDNRB protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [TNF protein results in increased expression of EDNRB protein]PMID:18718921 PMID:22207076
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