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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736761
Species: Mus musculus
RGD Object: Gene
Symbol: Atf2
Name: activating transcription factor 2
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf2increases expressionISOAtf2 (Rattus norvegicus)6480464CTDStreptozocin results in increased expression of ATF2 proteinPMID:26499206
Atf2multiple interactionsISOAtf2 (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein]PMID:26499206
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