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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735545
Species: Mus musculus
RGD Object: Gene
Symbol: Neurod1
Name: neurogenic differentiation 1
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Neurod1decreases expressionEXP 6480464CTDStreptozocin results in decreased expression of NEUROD1 mRNAPMID:24781736 PMID:29935216
Neurod1multiple interactionsEXP 6480464CTD[Streptozocin co-treated with bisphenol A] results in decreased expression of NEUROD1 mRNA; octylphenol inhibits the reaction [Streptozocin results in decreased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of NEUROD1 mRNA]PMID:24781736 PMID:29935216
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