GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | G6pc1 | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of G6PC1 mRNA | PMID:34896238 | G6pc1 | multiple interactions | EXP | | 6480464 | CTD | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA] | PMID:25446853 PMID:26522834 PMID:27769711 PMID:34896238 | G6pc1 | decreases activity | ISO | G6pc1 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in decreased activity of G6PC1 protein | PMID:26616445 | G6pc1 | decreases expression | ISO | G6pc1 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in decreased expression of G6PC1 mRNA | PMID:25905778 | G6pc1 | increases activity | ISO | G6pc1 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in increased activity of G6PC1 protein | PMID:22960630 PMID:25641191 PMID:26944432 | G6pc1 | increases expression | ISO | G6pc1 (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein | PMID:12446591 PMID:19634143 PMID:27038876 PMID:36627075 | G6pc1 | multiple interactions | ISO | G6pc1 (Rattus norvegicus) | 6480464 | CTD | 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein] | PMID:12446591 PMID:19634143 PMID:22960630 PMID:25641191 PMID:26616445 PMID:26944432 PMID:27038876 PMID:36627075 | | ||||||||||||||||||||||
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