GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYBB | increases expression | ISO | Cybb (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in increased expression of CYBB protein | PMID:19957251 | CYBB | increases expression | ISO | Cybb (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein | PMID:21381899 PMID:29420703 | CYBB | multiple interactions | ISO | Cybb (Rattus norvegicus) | 6480464 | CTD | [Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein] | PMID:35085591 | CYBB | multiple interactions | ISO | Cybb (Mus musculus) | 6480464 | CTD | 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein] | PMID:21381899 PMID:29420703 PMID:37120126 | | ||||||||||||||||||||||
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