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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11125
Species: Mus musculus
RGD Object: Gene
Symbol: Pmp22
Name: peripheral myelin protein 22
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmp22decreases expressionISOPmp22 (Rattus norvegicus)6480464CTDStreptozocin results in decreased expression of PMP22 mRNAPMID:17187935
Pmp22multiple interactionsISOPmp22 (Rattus norvegicus)6480464CTDProgesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA]PMID:17187935
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