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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDStreptozocin results in decreased expression of ESR2 mRNA

PMID:24781736
multiple interactionsEXP 6480464CTDbisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA], Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA], octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]

PMID:24781736
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.