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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620925
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1a
Name: PPARG coactivator 1 alpha
Acc ID: CHEBI:92875
Term: 5-(2-chloroethyl)-4-methylthiazole
Definition: A thiazole that has formula C6H8ClNS.
Chemical ID: MESH:D002719
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1amultiple interactionsISOPpargc1a (Mus musculus)6480464CTDChlormethiazole affects the reaction [Ethanol results in decreased expression of PPARGC1A mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in decreased acetylation of PPARGC1A protein]PMID:24892905
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