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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1298347
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP7
Name: caspase 7
Acc ID: CHEBI:9241
Term: spironolactone
Definition: A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Chemical ID: MESH:D013148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP7increases activityEXP 6480464CTDSpironolactone results in increased activity of CASP7 proteinPMID:22700542
CASP7multiple interactionsEXP 6480464CTDPalmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP7 protein]PMID:22700542
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