GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bid | decreases expression | ISO | Bid (Mus musculus) | 6480464 | CTD | Sirolimus results in decreased expression of BID protein | PMID:18097008 | Bid | increases expression | ISO | Bid (Mus musculus) | 6480464 | CTD | Sirolimus results in increased expression of BID mRNA; Sirolimus results in increased expression of BID protein | PMID:19922502 | Bid | multiple interactions | ISO | BID (Homo sapiens) | 6480464 | CTD | [7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of BID protein | PMID:15767555 | Bid | multiple interactions | ISO | Bid (Mus musculus) | 6480464 | CTD | [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID mRNA; [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID protein | PMID:19922502 | | ||||||||||||||||||||||
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