Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3700
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Acc ID: CHEBI:9159
Term: sinensetin
Definition: A pentamethoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 3' and 4' respectively.
Chemical ID: MESH:C059295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco1a1decreases activityEXP 6480464CTDsinensetin results in decreased activity of SLCO1B1 protein

PMID:32259555
Slco1a1multiple interactionsEXP 6480464CTD[sinensetin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan

PMID:32259555
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.