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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nefl
Name: neurofilament light chain
Acc ID: CHEBI:91460
Term: KN-93
Definition: A sulfonamide resulting from the formal condensation of p-methoxybenzenesulfonic acid with the anilino nitrogen of 2-(aminomethyl)-N-(2-hydroxyethyl)aniline in which the hydrogens of the primary amino group have been replaced by methyl and p-chlorocinnamyl groups. KN-93 is a selective inhibitor of Ca(2+)/calmodulin-dependent protein kinase II.
Chemical ID: MESH:C072105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Neflmultiple interactionsEXP 6480464CTDKN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]PMID:21879721
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