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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:9130
Term: sevoflurane
Definition: An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Chemical ID: MESH:C009250
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9multiple interactionsEXP 6480464CTDMIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]]PMID:32147387
Mmp9increases expressionISOMMP9 (Homo sapiens)6480464CTDSevoflurane results in increased expression of MMP9 mRNAPMID:35953652
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDLipopolysaccharides inhibits the reaction [Sevoflurane results in decreased expression of MMP9 mRNA]PMID:35953652
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