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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a2
Name: collagen type I alpha 2 chain
Acc ID: CHEBI:91215
Term: 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
Definition: A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Chemical ID: MESH:C095284
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7309846480464CTD1H-(1, 2, 4)oxadiazolo(4, 3-a)quinoxalin-1-one results in decreased expression of COL1A2 mRNA

PMID:22543296
multiple interactionsISORGD:7309846480464CTD1H-(1, 2, 4)oxadiazolo(4, 3-a)quinoxalin-1-one inhibits the reaction [NOC 18 results in increased expression of COL1A2 mRNA]

PMID:22543296
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.