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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Acc ID: CHEBI:91091
Term: CHIR 99021
Definition: A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.
Chemical ID: MESH:C473711
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lgr5increases expressionISOLGR5 (Homo sapiens)6480464CTDChir 99021 results in increased expression of LGR5 mRNAPMID:26259606
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