Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	69259
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Axin2
Name:	axin 2

Acc ID:	CHEBI:9107
Term:	senecionine
Definition:	A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.
Chemical ID:	MESH:C009237

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Axin2	decreases expression	ISO	Axin2 (Mus musculus)	6480464	CTD	senecionine results in decreased expression of AXIN2 mRNA	PMID:31606820

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.