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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2903
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6st
Name: interleukin 6 cytokine family signal transducer
Acc ID: CHEBI:9107
Term: senecionine
Definition: A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.
Chemical ID: MESH:C009237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6stdecreases expressionISOIl6st (Mus musculus)6480464CTDsenecionine results in decreased expression of IL6ST proteinPMID:35357534
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