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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp7a1
Name: cytochrome P450 family 7 subfamily A member 1
Acc ID: CHEBI:9107
Term: senecionine
Definition: A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.
Chemical ID: MESH:C009237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp7a1decreases expressionEXP 6480464CTDsenecionine results in decreased expression of CYP7A1 mRNAPMID:24641316
Cyp7a1decreases expressionISOCyp7a1 (Mus musculus)6480464CTDsenecionine results in decreased expression of CYP7A1 mRNAPMID:31606820
Cyp7a1decreases expressionISOCYP7A1 (Homo sapiens)6480464CTDsenecionine results in decreased expression of CYP7A1 mRNAPMID:26100227
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