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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346751
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2B6
Name: cytochrome P450 family 2 subfamily B member 6
Acc ID: CHEBI:9086
Term: (-)-selegiline
Definition: A selegiline that has formula C13H17N.
Chemical ID: MESH:D012642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2B6decreases activityEXP 6480464CTDSelegiline results in decreased activity of CYP2B6 proteinPMID:25656918
CYP2B6multiple interactionsEXP 6480464CTDSelegiline inhibits the reaction [CYP2B6 protein results in increased hydroxylation of Bupropion]PMID:25656918
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