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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2609
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf2
Name: fibroblast growth factor 2
Acc ID: CHEBI:90748
Term: O-(chloroacetylcarbamoyl)fumagillol
Definition: A carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative.
Chemical ID: MESH:C066515
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf2decreases expressionISORGD:708226480464CTDO-(chloroacetylcarbamoyl)fumagillol results in decreased expression of FGF2 protein

PMID:12576464
Fgf2multiple interactionsISORGD:708226480464CTD[O-(chloroacetylcarbamoyl)fumagillol co-treated with docetaxel] results in decreased expression of FGF2 protein

PMID:12576464
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.