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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bnip3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:90721
Term: N-[3-(aminomethyl)benzyl]acetamidine
Definition: An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
Chemical ID: MESH:C104820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7338146480464CTD[N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]

PMID:19442826
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.