GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NQO1 | decreases expression | EXP | | 6480464 | CTD | SB 203580 results in decreased expression of NQO1 mRNA | PMID:27454768 | NQO1 | multiple interactions | EXP | | 6480464 | CTD | SB 203580 inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 protein]; SB 203580 inhibits the reaction [Plant Extracts results in increased expression of NQO1 protein]; SB 203580 inhibits the reaction [Quercetin results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 protein] | PMID:16920990 PMID:27454768 PMID:30626086 | NQO1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of NQO1 mRNA]; SB 203580 promotes the reaction [Copper results in increased expression of NQO1 mRNA]; SB 203580 promotes the reaction [Lead results in increased expression of NQO1 mRNA] | PMID:18752316 PMID:28329830 PMID:31029725 | |
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