GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MMP2 | decreases expression | EXP | | 6480464 | CTD | SB 203580 results in decreased expression of MMP2 | PMID:23707804 | MMP2 | multiple interactions | EXP | | 6480464 | CTD | brazilein promotes the reaction [SB 203580 results in decreased expression of and results in decreased activity of MMP2 protein]; SB 203580 affects the reaction [U 0126 promotes the reaction [Plant Extracts results in decreased expression of MMP2 protein]]; SB 203580 inhibits the reaction [benz(a)anthracene results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP2 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP2 protein]]; SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [taiwanin E results in decreased expression of MMP2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; SB 203580 promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein]; SB 203580 promotes the reaction [Resveratrol results in decreased expression of and results in decreased activity of MMP2 protein]; SB 203580 promotes the reaction [Resveratrol results in decreased expression of MMP2]; SB 203580 results in decreased expression of and results in decreased activity of MMP2 protein | PMID:20599481 PMID:21635667 PMID:23707804 PMID:24841706 PMID:24929186 PMID:25605016 PMID:26179980 PMID:27807932 PMID:28181379 | MMP2 | affects expression | ISO | Mmp2 (Rattus norvegicus) | 6480464 | CTD | SB 203580 affects the expression of MMP2 mRNA; SB 203580 affects the expression of MMP2 protein | PMID:16575906 | |
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