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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:90705
Term: SB 203580
Definition: A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.
Chemical ID: MESH:C093642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1decreases expressionISOCOL1A1 (Homo sapiens)6480464CTDSB 203580 results in decreased expression of COL1A1 mRNAPMID:27235791
Col1a1multiple interactionsISOCol1a1 (Rattus norvegicus)6480464CTDSB 203580 inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]PMID:12065697
Col1a1multiple interactionsISOCOL1A1 (Homo sapiens)6480464CTDSB 203580 inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]PMID:18253093
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