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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10967
Species: Mus musculus
RGD Object: Gene
Symbol: Nedd4
Name: neural precursor cell expressed, developmentally down-regulated 4
Acc ID: CHEBI:90705
Term: SB 203580
Definition: A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.
Chemical ID: MESH:C093642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nedd4multiple interactionsISONEDD4 (Homo sapiens)6480464CTDSB 203580 inhibits the reaction [fulvestrant promotes the reaction [NEDD4 protein binds to and results in increased ubiquitination of GJA1 protein]]PMID:29180066
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