A member of the class of anthrapyrazoles that is anthra[1,9-cd]pyrazole substituted at position 6 by an oxo group. An inhibitor of c-Jun N-terminal kinase.
Chemical ID:
MESH:C432165
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[pyrazolanthrone co-treated with 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride] inhibits the reaction [Folic Acid results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone affects the reaction [TALDO1 gene mutant form promotes the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [flufenoxuron results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Folic Acid results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [pseudolaric acid B results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Triclosan results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone results in decreased phosphorylation of and results in decreased activity of MAPK8 protein
[cypermethrin co-treated with pyrazolanthrone] results in decreased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [cypermethrin results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; pyrazolanthrone inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein]
pyrazolanthrone inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein]; pyrazolanthrone inhibits the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [cinnamaldehyde results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [cordycepin results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK8 protein modified form]; pyrazolanthrone inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [LY 293111 results in increased expression of MAPK8 protein modified form]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [pachastrissamine analog results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [polyphyllin I results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Resveratrol results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; pyrazolanthrone inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone promotes the reaction [dehydrocrenatidine results in decreased phosphorylation of MAPK8 protein]
