GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fas | increases activity | ISO | FAS (Homo sapiens) | 6480464 | CTD | pyrazolanthrone results in increased activity of FAS protein | PMID:16061660 | Fas | increases expression | ISO | FAS (Homo sapiens) | 6480464 | CTD | pyrazolanthrone results in increased expression of FAS protein | PMID:16061660 | Fas | multiple interactions | ISO | FAS (Homo sapiens) | 6480464 | CTD | pyrazolanthrone inhibits the reaction [FGF7 protein results in increased expression of FAS protein]; pyrazolanthrone promotes the reaction [FAS protein results in increased cleavage of and results in increased activity of CASP3 protein]; pyrazolanthrone promotes the reaction [FAS protein results in increased cleavage of and results in increased activity of CASP8 protein] | PMID:16061660 PMID:16162944 | |
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