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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359092
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Krt10
Name: keratin 10
Acc ID: CHEBI:90633
Term: perfluorododecanoic acid
Definition: A fluoroalkanoic acid that is dodecanoic acid in which all of the hydrogens attached to carbon atoms are replaced by fluorines. It is a highly persistent, bioaccumulative breakdown product of stain- and grease-proof coatings on food packaging, soft furnishings and carpets.
Chemical ID: MESH:C522391
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDperfluorododecanoic acid results in decreased expression of KRT10 protein

PMID:19854247
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.