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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351708
Species: Homo sapiens
RGD Object: Gene
Symbol: TYRP1
Name: tyrosinase related protein 1
Acc ID: CHEBI:9055
Term: scoparone
Definition: A member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities.
Chemical ID: MESH:C018145
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TYRP1increases expressionISOTyrp1 (Mus musculus)6480464CTDscoparone results in increased expression of TYRP1 mRNAPMID:17049123
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