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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:8927
Term: S-(2,4-dinitrophenyl)glutathione
Definition: A glutathione conjugate in which the thiol hydrogen of glutathione has been replaced by a 2,4-dinitrophenyl group.
Chemical ID: MESH:C030190
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1affects exportISORGD:13446246480464CTDABCC1 protein affects the export of S-2 4-dinitrophenylglutathione

PMID:15041478
Abcc1affects transportISORGD:13446246480464CTDABCC1 protein affects the transport of S-2 4-dinitrophenylglutathione

PMID:16004972
Abcc1increases exportISORGD:13446246480464CTDABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione

PMID:16156793
Abcc1multiple interactionsISORGD:13446246480464CTDflavone inhibits the reaction [ABCC1 protein affects the export of S-2 4-dinitrophenylglutathione] hesperetin inhibits the reaction [ABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione] Mefloquine inhibits the reaction [ABCC1 protein affects the transport of S-2 4-dinitrophenylglutathione] naringenin inhibits the reaction [ABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione] Quercetin inhibits the reaction [ABCC1 protein affects the export of S-2 4-dinitrophenylglutathione] Quercetin inhibits the reaction [ABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione] resveratrol inhibits the reaction [ABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione] Silymarin inhibits the reaction [ABCC1 protein results in increased export of S-2 4-dinitrophenylglutathione] taxifolin inhibits the reaction [ABCC1 protein affects the export of S-2 4-dinitrophenylglutathione] verlukast inhibits the reaction [ABCC1 protein affects the transport of S-2 4-dinitrophenylglutathione]

PMID:15041478 PMID:16004972 PMID:16156793
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