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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345835
Species: Homo sapiens
RGD Object: Gene
Symbol: EIF2AK2
Name: eukaryotic translation initiation factor 2 alpha kinase 2
Acc ID: CHEBI:8891
Term: Roridin A
Definition: A trichothecene that has formula C29H40O9.
Chemical ID: MESH:C038849
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EIF2AK2increases expressionISOEif2ak2 (Mus musculus)6480464CTDroridin A results in increased expression of EIF2AK2 mRNAPMID:17483119
EIF2AK2multiple interactionsISOEif2ak2 (Mus musculus)6480464CTDlipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of EIF2AK2 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of EIF2AK2 mRNA]PMID:17483119
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