GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ache | affects activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Rivastigmine affects the activity of ACHE protein | PMID:12111444 | Ache | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Rivastigmine results in decreased activity of ACHE protein | PMID:15135892 PMID:18571635 PMID:19345205 PMID:30588862 | Ache | decreases activity | ISO | ACHE (Homo sapiens) | 6480464 | CTD | Rivastigmine results in decreased activity of ACHE protein | PMID:32092302 PMID:33037899 | Ache | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | AFDX 384 affects the reaction [Rivastigmine affects the activity of ACHE protein]; Rivastigmine inhibits the reaction [[Botulinum Toxins, Type A results in increased expression of and results in increased activity of ACHE protein] which results in decreased abundance of Acetylcholine]; Rivastigmine inhibits the reaction [Aluminum Chloride results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Aluminum Chloride results in increased expression of ACHE mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein] | PMID:12111444 PMID:32805344 PMID:34663170 PMID:37507053 | |
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