GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | increases export | EXP | | 6480464 | CTD | ABCB1A protein results in increased export of Risperidone | PMID:16118767 | Abcb1a | multiple interactions | EXP | | 6480464 | CTD | Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Risperidone] | PMID:16118767 | Abcb1a | affects abundance | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | ABCB1 gene polymorphism affects the abundance of Risperidone; ABCB1 protein affects the abundance of Risperidone | PMID:17541883 PMID:18708991 PMID:20563569 PMID:21449914 PMID:22623266 | Abcb1a | affects response to substance | ISO | Abcb1a (Mus musculus) | 6480464 | CTD | ABCB1A protein affects the susceptibility to Risperidone | PMID:15502009 | Abcb1a | affects response to substance | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | ABCB1 gene polymorphism affects the susceptibility to Risperidone; ABCB1 protein affects the susceptibility to Risperidone | PMID:17054409 | Abcb1a | decreases activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Risperidone results in decreased activity of ABCB1 protein | PMID:16810505 PMID:16936711 | Abcb1a | increases export | ISO | Abcb1a (Mus musculus) | 6480464 | CTD | ABCB1A protein results in increased export of Risperidone | PMID:16118767 | Abcb1a | increases response to substance | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | ABCB1 protein results in increased susceptibility to Risperidone | PMID:19997080 | Abcb1a | increases transport | ISO | Abcb1a (Mus musculus) | 6480464 | CTD | ABCB1A protein results in increased transport of Risperidone | PMID:22691713 | Abcb1a | increases transport | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | ABCB1 protein results in increased transport of Risperidone | PMID:22691713 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin] | PMID:16936711 | |
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