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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10436
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:88542
Term: Butylparaben
Definition: null
Chemical ID: MESH:C038091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1decreases activityISOCyp1a1 (Rattus norvegicus)6480464CTDbutylparaben results in decreased activity of CYP1A1 proteinPMID:27432241
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTD[butylparaben co-treated with triclocarban] results in increased expression of CYP1A1 mRNAPMID:23524099
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