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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733968
Species: Homo sapiens
RGD Object: Gene
Symbol: IKBKB
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Acc ID: CHEBI:88522
Term: Monobutylphthalate
Definition: A phthalic acid monoester that has formula C12H14O4.
Chemical ID: MESH:C028577
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IKBKBincreases expressionISOIkbkb (Rattus norvegicus)6480464CTDmonobutyl phthalate results in increased expression of IKBKB mRNAPMID:20864626
IKBKBincreases phosphorylationISOIkbkb (Mus musculus)6480464CTDmonobutyl phthalate results in increased phosphorylation of IKBKB proteinPMID:26745512
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