Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733129
Species: Mus musculus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:88522
Term: Monobutylphthalate
Definition: A phthalic acid monoester that has formula C12H14O4.
Chemical ID: MESH:C028577
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimdecreases methylationEXP 6480464CTDmonobutyl phthalate results in decreased methylation of VIM promoterPMID:26745512
Vimincreases expressionEXP 6480464CTDmonobutyl phthalate results in increased expression of VIM mRNA; monobutyl phthalate results in increased expression of VIM proteinPMID:20553848 PMID:26745512 PMID:28735033
Vimmultiple interactionsEXP 6480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [monobutyl phthalate results in increased expression of VIM protein]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM protein]; S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM protein]; VIM affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]; VIM affects the reaction [[monobutyl phthalate co-treated with Colforsin] results in increased secretion of Progesterone]; VIM inhibits the reaction [RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]]PMID:26745512 PMID:28735033
Go Back to source page   Continue to Ontology report