GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CCND1 | increases response to substance | EXP | | 6480464 | CTD | CCND1 mutant form results in increased susceptibility to BMS 754807 | PMID:24986516 | CCND1 | multiple interactions | EXP | | 6480464 | CTD | [BMS 754807 co-treated with palbociclib] results in increased expression of CCND1 protein; [CCND1 mutant form results in increased susceptibility to BMS 754807] which results in decreased phosphorylation of RPS6KB1 protein | PMID:24986516 | |
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